insulin medication side effects

The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. [Ref], Adverse reactions reported with this insulin include hypoglycemia, allergic reactions, injection site reactions, lipodystrophy, weight gain, and edema[Ref], Rare (less than 0.1%): Insulin resistance, Frequency not reported: Hypokalemia, hyperglycemia, diabetic ketoacidosis, hyperosmolar hyperglycemic non-ketotic syndrome, hypomagnesemia, hypophosphatemia. Treatment involves hospitalization, IV fluids and insulin. Note: This document contains side effect information about insulin isophane. Over the long-term, improved glycemic control decreases the risk for neuropathy. Drug interactions (drug on drug side effects): Beta-blockers, clonidine and reserpine may mask some of the signs and symptoms of hypoglycemia. No diabetes medication is free from side effects, but these are some of the worst offenders. Hypokalemia, which is due to a shift in potassium from the extracellular to the intracellular space, occurs with all insulins. It is also used along with glucose to treat high blood potassium levels. Available for Android and iOS devices. [Ref], The most common adverse reactions reported with this insulin include hypoglycemia, allergic reactions, injection site reactions, lipodystrophy, weight gain, and edema. Subscribe to Drugs.com newsletters for the latest medication news, new drug approvals, alerts and updates. What are the side effects of the diabetes drug insulin? NovoMix 30: Insulin is a naturally occurring hormone made by the pancreas that helps our body use or store the glucose (sugar) it gets from food. Also, each type of insulin has its own profile of possible side effects. advice about side effects. Drug class: basal insulin; Drug form: liquid solution given by subcutaneous injection; Like other drugs, Tresiba can cause side effects. "Product Information. The timing of hypoglycemia generally reflects the time-action profile of the administered insulin, however, the time action profile of any insulin may vary considerably in different individuals or at different times in the same individual depending on dose, site of injection, blood supply, temperature, and physical activity. Rapid-acting insulin starts to work almost immediately after you inject it. Changing to insulin can actually be a lot better. The drug interactions can vary — some cause the insulin to work less well, while others cause side effects to become more severe. Hypokalemia, which is due to a shift in potassium from the extracellular to the intracellular space, occurs with all insulins. Get emergency medical help if you have signs of insulin allergy: redness, swelling, sweating, itchy skin rash over the entire body, trouble breathing, fast heartbeats, feeling like you might pass out, or swelling in your tongue or throat. These side effects may go away during treatment as your body adjusts to the medicine. Hypokalemia and hypomagnesemia has been reported, particularly in patients treated for diabetic ketoacidosis (DKA). 1. Generic Name: insulin isophane Medically reviewed by Drugs.com. Data sources include IBM Watson Micromedex (updated 3 Mar 2021), Cerner Multum™ (updated 1 Mar 2021), ASHP (updated 3 Mar 2021) and others. Below is a list of medications that can interact with insulin regular (human). [Ref], Uncommon (0.1% to 1%): Local reactions such as redness, swelling, or itching at the injection site, Very rare (less than 0.01%): Anaphylactic reactions, Postmarketing reports: Severe, life-threatening, generalized allergy, including anaphylaxis[Ref]. What is the difference between regular insulin and lispro (Humalog)? In situations in which not enough insulin is available to control blood glucose, hyperglycemia, diabetic ketoacidosis, and hyperosmolar hyperglycemic non-ketotic syndrome may occur. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances. Lilly, Eli and Company, Indianapolis, IN. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. Some side effects may not be reported. [Ref], Uncommon (0.1% to 1%): Local reactions such as redness, swelling, or itching at the injection site, Very rare (less than 0.01%): Anaphylactic reactions[Ref], Hypersensitivity side effects have included both local and systemic reactions. Cerner Multum, Inc. "UK Summary of Product Characteristics." Most minor reactions to insulin at the injection site resolve in a few days to a few weeks. These side effects may go away during treatment as your body adjusts to the medicine. Basal insulin is the insulin that keeps your blood sugar steady all day. Applies to insulin isophane: subcutaneous suspension, Frequency not reported: Sodium retention and edema[Ref], Insulin may cause sodium retention and edema, especially with intensified insulin therapy. O 0, 3. It may cause you to hang on to fluids in your body, which can lead to swelling. Last updated on April 26, 2020. In situations in which not enough insulin is available to control blood glucose, hyperglycemia, diabetic ketoacidosis, and hyperosmolar hyperglycemic non-ketotic syndrome may occur. For instance, some can interfere with how well a drug works, while others can cause increased side effects. O 0. Some people with type 2 diabetes can benefit from using both medication and insulin. You may report them to the FDA. 2. Other Possible Insulin Side Effects. [Ref], Uncommon (0.1% to 1%): Lipodystrophy[Ref], Long-term use of insulin can cause lipodystrophy at the site of repeated insulin injections. Other factors such as changes in food intake (timing of meals, amount or type of food) and concomitant medications will also affect the risk of hypoglycemia. Although not all of these side effects may occur, if they do occur they may need medical attention. Insulin human regular is a short-acting type of insulin. Regular insulin side effects. The clinical significance of these antibodies is unknown; it does not appear to cause deterioration in glycemic control. A person with diabetes who has hyperglycemia frequently or for long periods of time may suffer damage to the blood vessels, nerves, and organs. Medically reviewed by Drugs.com. Side effects not requiring immediate medical attention. [Ref], Frequency not reported: Acute painful peripheral neuropathy[Ref], Weight gain can occur with insulin use; it is believed to be due to the anabolic effects of insulin and the decrease in glycosuria.[Ref]. O 0. Consumer; Side effects; Professional; FAQ; Note: This document contains side effect information about insulin isophane. Some side effects may not be reported. You may also report side effects at https://www.fda.gov/medwatch. Anaphylaxis has been reported. Check with your doctor immediately if any of the following side effects occur: More common. Available for Android and iOS devices. [Ref], Transitory, reversible ophthalmologic refraction disorder and worsening of diabetic retinopathy has been reported with insulin initiation and glucose control intensification. Common side effects of insulin include hypoglycemia, headache, weight gain, rash, itching, flu-like symptoms, lipoatrophy, and reaction at the site of injection. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Lantus (insulin glargine) is a man-made injectable form of insulin used to regulate sugar (glucose) levels in type 1 and type 2 diabetes. What are the side effects? Like all medications, you need to take insulin in the right amounts. [Ref], Increases in titers of anti-insulin antibodies that react with human insulin have been observed; some data indicates the increase is transient. They usually occurred within the first two weeks of therapy and then disappear. Drug information provided by: IBM Micromedex. We comply with the HONcode standard for trustworthy health information -. The clinical significance of these antibodies is unknown; it does not appear to cause deterioration in glycemic control. metformin, Trulicity, Victoza, Tresiba, Lantus, Levemir, Humalog, sodium bicarbonate, Novolog, Basaglar. [Ref], Acute painful peripheral neuropathy has been reported with insulin initiation and glucose control intensification. Insulin was formerly used in a psychiatric treatment called insulin shock therapy.. Side effects Allergy. In some instances these reactions have been caused by other factors such as irritants in a skin cleansing agent or poor injection technique. Insulin increases the intracellular transport of phosphate, which often results in hypophosphatemia during treatment of DKA. You may report side effects to FDA at 1-800-FDA-1088. NovoLIN R (insulin regular)." These side effects may go away during treatment as your body adjusts to the medicine. Humulin R (insulin regular)." Lipodystrophy includes lipohypertrophy (thickening of adipose tissue) and lipoatrophy (thinning of adipose tissues). Hypersensitivity reactions have included both local and systemic reactions. Our Lantus (insulin glargine [rdna origin]) Injection Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication. It only works for 2 to 4 hours. These drugs boost the way insulin works in the body. Common side effects of Lantus include decreased blood sugar, injection site reactions, water retention in the joints, and weight gain. Hypoglycemia is the most common adverse reaction of all insulin therapies. metformin, Trulicity, Victoza, Tresiba, Lantus, Levemir, Novolog, Basaglar, Toujeo, insulin regular. Lilly, Eli and Company, Indianapolis, IN. Other side effects include: weight gain. Some of the dosage forms listed on this page may not apply to the brand name NPH Insulin.. For the Consumer These usually resolve in a few days to a few weeks; rotation of the injection site reduces the risk of these reactions developing. These usually resolve in a few days to a few weeks; rotation of the injection site reduces the risk of these reactions developing. SLIDESHOW … Insulin is one of many hormones that help the body turn the food we eat into energy. Along with its needed effects, a medicine may cause some unwanted effects. Continued. Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. True allergy to insulin has been rare, and sensitization was usually associated with specific animal proteins in bovine and less pure forms of porcine insulins. Call your doctor for medical advice about side effects. Although not all of these side effects may occur, if they do occur they may need medical attention. Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. NPH Insulin Side Effects. Unfortunately, insulin can cause weight gain, interactions with other medications, headaches, and nausea. This medication may be available under multiple brand names and/or in several different forms. [Ref], Frequency not reported: Acute painful peripheral neuropathy[Ref], Weight gain can occur with insulin use; it is believed to be due to the anabolic effects of insulin and the decrease in glucosuria.[Ref]. There are various side effects that occur from insulin. Side effects not requiring immediate medical attention. Children may be more sensitive to the side effects of this drug, especially low blood sugar. Long-Term Dangers. Other factors such as changes in food intake (timing of meals, amount or type of food) and concomitant medications will also affect the risk of hypoglycemia. Humulin N (insulin isophane)." Which type of insulin has the longest duration of action? If you have questions about side effects, call your doctor. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them: Applies to insulin regular: injectable solution, intravenous solution, subcutaneous solution, Transitory, reversible ophthalmologic refraction disorder and worsening of diabetic retinopathy has been reported with insulin initiation and glucose control intensification. You may report them to the FDA. Hypoglycemia is the most common adverse reaction of all insulin therapies. Some side effects of liraglutide may occur that usually do not need medical attention. "Product Information. Over the long-term, improved glycemic control decreases the risk for diabetic neuropathy. Cerner Multum, Inc. "Australian Product Information." "Product Information. The change can have upsides, particularly for patients who have been on a complicated regimen of three or four drugs, with lots of side effects. Below, we describe certain interactions and the drugs … Common side effects of insulin. We comply with the HONcode standard for trustworthy health information -. [Ref], Frequency not reported: Transitory, reversible ophthalmologic refraction disorder, worsening diabetic neuropathy[Ref], Uncommon (0.1% to 1%): Lipodystrophy[Ref], Long-term use of insulin can cause lipodystrophy at the site of repeated insulin injections. Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. Side Effects. However, some patients experience an interference with … Insulin is used to treat a number of diseases including diabetes and its acute complications such as diabetic ketoacidosis and hyperosmolar hyperglycemic states. There are several types, preparations, and dosage amounts of insulin. This is not a complete list of side effects and others may occur. Hypokalemia and hypomagnesemia has been reported, particularly in patients treated for diabetic ketoacidosis (DKA). Consult your doctor before taking Lantus if pregnant or breastfeeding. 4. The right dosage will provide benefit without harm. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. Combination use with thiazolidinediones has resulted in fluid retention which has led to or exacerbated heart failure. help if any of these side effects or any other side effects bother you or do not go away: These are not all of the side effects that may occur. Can regular and lispro insulin (Humalog) be mixed? [Ref], Frequency not reported: Transitory, reversible ophthalmologic refraction disorder, worsening diabetic neuropathy[Ref], Common (1% to 10%): Injection site hypertrophy, Frequency not reported: Injection site reactions[Ref], Injection site reactions including pain, redness, hives, inflammation, bruising, swelling, and itching have occurred. [Ref], Frequency not reported: Formation of anti-insulin antibodies[Ref], Rare (less than 0.1%): Insulin resistance, Frequency not reported: Hypokalemia, hyperglycemia, diabetic ketoacidosis, hyperosmolar hyperglycemic non-ketotic syndrome, hypomagnesemia, hypophosphatemia[Ref]. Tell your It puts people at risk for: Some pills to treat diabetes include: Biguanides. Check with your doctor immediately if any of the following side effects occur while taking insulin regular: Some side effects of insulin regular may occur that usually do not need medical attention. Lipodystrophy includes lipohypertrophy (thickening of adipose tissue) and lipoatrophy (thinning of adipose tissues). Call your doctor for medical advice about side effects. Ketoacidosis is a more common occurrence with type 1 diabetes. Weight gain has been reported and has been attributed to the anabolic effects of insulin and the decrease in glucosuria. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. Last updated on Nov 16, 2020. puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue, Bleeding, blistering, burning, coldness, discoloration of the skin, feeling of pressure, hives, infection, inflammation, itching, lumps, numbness, pain, rash, redness, scarring, soreness, stinging, swelling, tenderness, tingling, ulceration, or warmth at the injection site, redistribution or accumulation of body fat. This is not a complete list of side effects and others may occur. 4. The timing of hypoglycemia generally reflects the time-action profile of the administered insulin, however, the time action profile of any insulin may vary considerably in different individuals or at different times in the same individual depending on dose, site of injection, blood supply, temperature, and physical activity. [Ref], Increases in titers of anti-insulin antibodies that react with human insulin have been observed; some data indicates the increase is transient. The main side effects of insulin have to do with taking too little or too much of the drug. Side effects, such as upset stomach and decreased appetite, are generally mild. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances. NovoLIN N (insulin isophane (NPH))." Over the long-term, improved glycemic control decreases the risk for neuropathy. Commonly reported side effects of insulin regular include: hypoglycemia. For people with diabetes, either the pancreas does not make enough insulin to meet the body's requirements, or the body cannot properly use the insulin that is made. Applies to insulin regular: injection solution. Any specific brand name of this medication may not be available in all of the forms or approved for all of the conditions discussed here. Novo Nordisk Pharmaceuticals Inc, Princeton, NJ. Side effects include nausea, hunger, headache, blurred vision, irritability, heart palpitations, and tremors. Subscribe to Drugs.com newsletters for the latest medication news, new drug approvals, alerts and updates. Call your doctor for medical Data sources include IBM Watson Micromedex (updated 3 Mar 2021), Cerner Multum™ (updated 1 Mar 2021), ASHP (updated 3 Mar 2021) and others. Along with its needed effects, insulin regular may cause some unwanted effects. Drug information provided by: IBM Micromedex. Novo Nordisk Pharmaceuticals Inc, Princeton, NJ. Applies to insulin isophane: subcutaneous suspension, subcutaneous suspension pen-injector. Cerner Multum, Inc. "Australian Product Information." [Ref], Common (1% to 10%): Injection site hypertrophy, Frequency not reported: Injection site reactions[Ref], Injection site reactions including pain, redness, hives, inflammation, bruising, swelling, and itching have occurred. WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. doctor or get medical help right away if you have any of the following signs or symptoms that may be related to a very bad side effect: All drugs may cause side effects. Insulin increases the intracellular transport of phosphate, which often results in hypophosphatemia during treatment of DKA. [Ref], Frequency not reported: Formation of anti-insulin antibodies[Ref], Frequency not reported: Sodium retention and edema[Ref], Insulin may cause sodium retention and edema, especially with intensified insulin therapy. Generalized allergy to insulin may present as a whole body rash, dyspnea, wheezing, hypotension, tachycardia, or diaphoresis. These reactions are becoming rare (less than 1% of patients) due to the use of purer forms of pork insulin or biosynthetic human insulin. 1. Medically reviewed by Drugs.com. HumuLIN R; HumuLIN R U-100 ; NovoLIN R; Descriptions. Last updated on Nov 16, 2020. When taken with great care and careful management, insulin is a critical part of what keeps you alive and healthy. Low blood sugar Some of the dosage forms listed on this page may not apply to the brand name NPH Insulin. The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. Some side effects of insulin regular may occur that usually do not need medical attention. "Product Information. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Call your doctor or get medical The former can result in high blood sugar, or hyperglycemia. US Brand Name. However, many people have no side effects or only have minor side effects. Signs of an allergic reaction, like rash; Thick skin, pits, or lumps where the injection was given. Warnings, precautions, and drug interactions should be reviewed prior to taking insulin. ... (such as diet and medications including insulin). 2. Local reactions have presented as erythema, swelling, heat, or subcutaneous nodules. Keep in mind that most of the side effects of insulin are actually the result of inaccurate doses and improper injection practices. Cerner Multum, Inc. "UK Summary of Product Characteristics." Low blood sugar (hypoglycemia) is a side effect of all forms of insulin. O 0, 3. SLIDESHOW … Local reactions have presented as erythema, local edema, and pruritus at the injection site. A slow erosion of health is the silent, insidious danger of not taking medications as necessary for type 1 or type 2 diabetes. Corticosteroids, thyroid supplements, estrogens, isoniazid, niacin, phenothiazines and rifampin may increase insulin requirements. You may report side effects to FDA at 1-800-FDA-1088. Combination use with thiazolidinediones has resulted in fluid retention which has led to or exacerbated heart failure. See below for a comprehensive list of adverse effects. Localized reactions have been reported with metacresol, which is an excipient in many insulin products. You may report side effects to the FDA at 1-800-332-1088. [Ref], Acute painful peripheral neuropathy has been reported with insulin initiation and glucose control intensification. Drugs and Supplements Insulin Human Regular (Injection Route) Description and Brand Names. Insulin is a medication prescribed to treat type 1 diabetes and type 2 diabetes mellitus. Our Humulin R (insulin (human recombinant)) Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication. Over the long-term, improved glycemic control decreases the risk for diabetic neuropathy. Insulin is the oldest medication for diabetes and is usually well tolerated by most people. Biguanides (Metformin) Biguanides lower blood sugar by decreasing the amount of sugar made by the liver, thus decreasing the need for insulin. Insulin aspart should be used along with an intermediate or long-acting insulin.

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